Dr. Thiyagu Rajakannan

Dr. Thiyagu Rajakannan is a Research Associate in IMPAQ International’s Health Division. He has more than six years of experience in designing and conducting both quantitative and qualitative analyses for Clinical, Health Policy, and Pharmacoepidemiology research using large administrative claim databases, clinical trial registries, electronic medical records, and health care survey data.


Dr. Rajakannan is skilled in Pharmacoepidemiology, Clinical Pharmacology, Health Policy Research, R, and SAS. He is proficient in the various phases of the project lifecycle including the strategic plan, literature review, compiling of existing data, proposal development, study design, data management, statistical analysis, publication, and presentation.

Prior Experience

Prior to joining IMPAQ, Dr. Rajakannan was a Research Fellow at, NIH, one of the world’s largest clinical trial registries that provides patients, their family members, health care professionals, researchers, and the public with easy access to information on publicly and privately supported clinical studies on a wide range of diseases and conditions.

While there, Dr. Rajakannan was involved in leading research projects, policy development, and information updates on clinical trials and protocol registration and results system (PRS). Dr. Rajakannan also evaluated laws and policies related to the registration and results reporting in


Dr. Rajakannan earned his Ph.D. from the Manipal University, specialized in Pharmacoepidemiology, Patient Safety, and Health Policy. He has published and/or presented more than 50 papers on his work.

Previous Papers and Presentations

Rajakannan, T., Fain, K. M., Williams, R. J., Tse, T. & Zarin, D. A. (2017). Reporting of Sex and Gender in Clinical Trial Protocols and Published Results. International Congress on Peer Review and Scientific Publication.

Fain, M. K., Rajakannan, T., Tse, T., Williams, R. J. & Zarin, D. A. (2018) Results Reporting for trials with the same sponsor, drug and condition in and Peer-reviewed publications. JAMA Internal Medicine, 178(7), 990-992.

Zarin, Z.A., Tse, T., Williams, R. & Rajakannan, T. (2017) The Status of Trial Registration Eleven Years after the ICMJE Policy. New England Journal of Medicine, 376(4), 383-391.

Rajakannan, T., Safer, D. J., Burcu, M. & Zito, J. M. (2016) National Trends in Psychiatric Not Otherwise Specified (NOS) Diagnosis and Medication Use among Adults in Outpatient Treatment. Psychiatric Services, 67(3), 289-295.

Guddattu, V., Rao, A. K. & Rajakannan, T. (2015) Comparison between count regression and binary logistic regression models in the analysis of adverse drug reaction data. ProbStat Forum, 8, 140-147.

Safer, D., Rajakannan, T., Burcu, M. & Zito, J. M. (2015) Trends in subthreshold psychiatric diagnoses for youth in community treatment. JAMA Psychiatry, 72(1), 75-83.

Rajakannan, T., Zito, J. M., Burcu, M. & Safer, D. (2014) Pediatric Bipolar Disorder: Subtype trend and impact of behavioral comorbidities. Journal of Clinical Medicine, 3(1), 310-322.

Rajakannan, T., Mallayasamy, S., Guddattu, V., Kamath, A., Vilakkthala, R., Rao, P. G. & Bairy, L. K. (2012) Cost of adverse drug reactions in a south Indian tertiary care teaching hospital. Journal of Clinical Pharmacology, 52(4), 559-65.

Rajakannan, T., Mallayasamy, S. R., Rajesh, V., Muralidhar, V., Smitha, P., Sudha, V. & Laxminarayana, B. K. (2010) Development of indicators for identifying adverse drug events in an Indian tertiary care teaching hospital. Journal of Drug, Healthcare and Patient Safety 2, 95-100.